Below is a list of all CanTest publications that acknowledge the support of Cancer Research UK

  1. Zimolzak AJ, Shahid U, Giardina TD, Memon SA, Mushtaq U, Zubkoff L, Murphy DR, Bradford A, Singh H. Why Test Results Are Still Getting “Lost” to Follow-up: a Qualitative Study of Implementation Gaps. Journal of General Internal Medicine, 2021. doi: 10.1007/s11606-021-06772-y
  2. Ward T, Medina-Lara A, Mujica-Mota RE, Spencer AE. Accounting for Heterogeneity in Resource Allocation Decisions: Methods and Practice in UK Cancer Technology Appraisals. Value Health, 2021; Jul;24(7):995-1008. doi: 10.1016/j.jval.2020.12.022.
  3. Saya S, McIntosh JG, Winship IM, Milton S, Clendenning M, Kyriakides M, Emery J, et al. Informed choice and attitudes regarding a genomic test to predict risk of colorectal cancer in general practice. Patient Education and Counseling, 2021. doi:10.1016/j.pec.2021.08.008
  4. Rubin G, Walter FM, Emery J, Hamilton W, Hoare Z, Howse J, Nixon C, Srivastava T, Thomas C, Ukoumunne OC, Usher-Smith JA, Whyte S, Neal RD. Electronic clinical decision support tool for assessing stomach symptoms in primary care (ECASS): a feasibility study. BMJ Open, 2021;11:e041795. doi: 10.1136/bmjopen-2020-041795
  5. Rajan, S, Baldwin, J, Giardina, T, Singh, H. Technology-Based Closed-Loop Tracking for Improving Communication and Follow-up of Pathology Results. Journal of Patient Safety, 2020. doi:10.1097/PTS.0000000000000759
  6. Price S, Abel GA, Hamilton W. Guideline interval: A new time interval in the diagnostic pathway for symptomatic cancer. Cancer Epidemiology, 2021; volume 73, 2021, 101969, ISSN 1877-7821. doi:10.1016/j.canep.2021.101969
  7. Nicholson, B.D., Oke, J.L., Aveyard, P. et al. Individual inflammatory marker abnormalities or inflammatory marker scores to identify primary care patients with unexpected weight loss for cancer investigation?. British Journal of Cancer, 2021;124, 1540–1542. doi:10.1038/s41416-021-01282-4
  8. Neal, R, Smith L. Urgent cancer referrals: how well are they working and can they be improved? British Journal of General Practice, 2021; 71 (710): 390-391. doi: 10.3399/bjgp21X716801
  9. Mwaka AD, Walter FM, Scott S, et al. Symptom appraisal, help-seeking and perceived barriers to healthcare seeking in Uganda: an exploratory study among women with potential symptoms of breast and cervical cancer. BMJ Open, 2021;11:e041365. doi: 10.1136/bmjopen-2020-041365
  10. Moodley J, Harries J, Scott SE, Mwaka AD, Saji S, Walter FM. Exploring primary care level provider interpretation and management of potential breast and cervical cancer signs and symptoms in South Africa. ecancer, 2021;15 1298. doi:10.3332/ecancer.2021.1298
  11. Milton, S., McIntosh, J., Macrae, F. et al. An RCT of a decision aid to support informed choices about taking aspirin to prevent colorectal cancer and other chronic diseases: a study protocol for the SITA (Should I Take Aspirin?) trial. Trials, 2021; 22, 452. doi:10.1186/s13063-021-05365-8
  12. Milton, S., McIntosh, J., Boyd, L. et al. Commentary: Pivoting during a pandemic: developing a new recruitment model for a randomised controlled trial in response to COVID-19. Trials, 2021; 22, 605. doi:10.1186/s13063-021-05567-0
  13. Merriel SWD, Ingle SM, May MT, Martin RM. Retrospective cohort study evaluating clinical, biochemical and pharmacological prognostic factors for prostate cancer progression using primary care data. BMJ Open, 2021;11:e044420. doi: 10.1136/bmjopen-2020-044420
  14. Martins T, Walter FM, Penfold C, Abel G, Hamilton W. Primary care use by men with symptoms of possible prostate cancer: A multi-method study with an ethnically diverse sample in London. European journal of cancer care, 2021. doi:10.1111/ecc.13482
  15. Mahajan P, Pai C, Cosby K, Mollen C, Shaw K, Chamberlain J, El-Kareh R, Ruddy R, Alpern E, Epstein H, Giardina T, Graber M, Medford-Davis L, Medlin R, Upadhyay D, Parker S, Singh H. Identifying trigger concepts to screen emergency department visits for diagnostic errors. Diagnosis, 2021;8(3): 340-346. doi:10.1515/dx-2020-0122
  16. Herbert A, Rafiq M, Pham TM, Renzi C, Abel GA, Price S, et al. Predictive values for different cancers and inflammatory bowel disease of 6 common abdominal symptoms among more than 1.9 million primary care patients in the UK: A cohort study. PLoS Med, 2021; 18(8): e1003708. doi:10.1371/journal.pmed.1003708
  17. Habgood E, McCormack C, Walter FM, Emery JD. Patients’ Experiences of Using Skin Self-monitoring Apps With People at Higher Risk of Melanoma: Qualitative Study. JMIR Dermatol 2021;4(2):e22583 doi: 10.2196/22583
  18. Funston G, Mounce LTA, Price S, Rous B, Crosbie EJ, Hamilton W, Walter FM.  CA125 test result, test-to-diagnosis interval, and stage in ovarian cancer at diagnosis: a retrospective cohort study using electronic health records. British Journal of General Practice, 2021; 71 (707): e465-e472. DOI: 10.3399/BJGP.2020.0859
  19. Funston G, Abel G, Crosbie EJ, Hamilton W, Walter FM. Could Ovarian Cancer Prediction Models Improve the Triage of Symptomatic Women in Primary Care? A Modelling Study Using Routinely Collected Data. Cancers, 2021. doi:10.3390/cancers13122886
  20. Disbeschl S, Surgey A, Roberts JL, Hendry A, Lewis R, Goulden N, Neal R, et al. Protocol for a feasibility study incorporating a randomised pilot trial with an embedded process evaluation and feasibility economic analysis of ThinkCancer!: a primary care intervention to expedite cancer diagnosis in Wales. Pilot and Feasibility Studies, 2021. doi:10.1186/s40814-021-00834-y
  21. Daniel M, Park S, Seifert CM, et al. Understanding diagnostic processes in emergency departments: a mixed methods case study protocol. BMJ Open, 2021. doi: 10.1136/bmjopen-2020-044194
  22. Danckert B, Zalounina Falborg A, Christensen NL, Frederiksen H, Lyratzopoulos G, McPhail S, Ryg J, Vedsted P, Thomsen LA, Jensen H. Routes to diagnosis and the association with the prognosis in patients with cancer – A nationwide register-based cohort study in Denmark. Cancer Epidemiology, 2021. doi:10.1016/j.canep.2021.101983
  23. Chapman D, Poirier V, Fitzgerald K, Nicholson BD, Hamilton W. Non-specific symptoms-based pathways for diagnosing less common cancers in primary care: a service evaluation. British Journal of General Practice, 2021 doi:10.3399/BJGP.2020.1108
  24. Bradley SH, Bhartia BS, Callister ME, Hamilton WT, Hatton NLF, Kennedy MP, Mounce L, Shinkins B, Neal R, et al. Chest X-ray sensitivity and lung cancer outcomes: a retrospective observational study. British Journal of General Practice, 2021. doi: 10.3399/BJGP.2020.1099
  25. Boennelykke A, Jensen H, Østgård LSG, Falborg AZ, Christensen KS, Hansen AT, Emery J, Vedsted P. Insufficient classification of anaemia in general practice: a Danish register-based observational study. Scandinavian Journal of Primary Health Care, 2021. doi:10.1080/02813432.2021.1958499
  26. Boennelykke A, Jensen H, Zalounina Falborg A, Østgård LSG, Hansen AT, Christensen KS & Vedsted P. Diagnostic workup of cancer in patients with new-onset anaemia: a Danish cohort study in general practice. Scandinavian Journal of Primary Health Care, 2021. doi: 10.1080/02813432.2021.1970934
  27. Bhartia B.S.K, Hatton N, Aslam R, Bradley SH, Darby M, Hamilton W, Hurst E, Kennedy M.P.T, Mounce L.T.A., Neal R.D., Shinkins B, Callister M.E.J. A prospective cohort evaluation of the sensitivity and specificity of the chest X-ray for the detection of lung cancer in symptomatic adults. European Journal of Radiology, 2021,
  28. Nicholson BD, Aveyard P, Koshiaris C, Perera R, Hamilton W, Oke J, et al. Combining simple blood tests to identify primary care patients with unexpected weight loss for cancer investigation: Clinical risk score development, internal validation, and net benefit analysis. PLoS Med, 2021 18(8): e1003728.
  29. Merriel SWD, Martins T, Bailey SER. Exploring the Causes of Death Among Patients With Metastatic Prostate Cancer – A Changing Landscape. JAMA Network Open, doi: 10.1001/jamanetworkopen.2021.20889
  30. Meyer AND, Giardina TD, Khawaja L, Singh H. Patient and clinician experiences of uncertainty in the diagnostic process: Current understanding and future directions. Patient Education and Counseling, 2021, doi: 10.1016/j.pec.2021.07.028
  31. Bradley SH, Nicholson BD, Funston G. Interpreting negative test results when assessing cancer risk in general practice. British Journal of General Practice, 2021, doi:
  32. Baun ML, Dueholm M, Heje HN, Hamilton W, Petersen LK, Vedsted P. Direct access from general practice to transvaginal ultrasound for early detection of ovarian cancer: a feasibility study. Scandinavian Journal of Primary Care Health, 2021, doi: 10.1080/02813432.2021.1922831
  33. Cheraghi-Sohi S, Holland F, Singh H, Danczak A, Esmail A, Morris RL, Small N, Williams R, de Wet C, Campbell SM, Reeves D. Incidence, origins and avoidable harm of missed opportunities in diagnosis: longitudinal patient record review in 21 English general practices. BMJ Quality & Safety, 2021, doi: 10.1136/bmjqs-2020-012594
  34. Archer S, Calanzani N, Honey S, Johnson M, Neal R, Scott SE, Walter FM. Impact of the COVID-19 pandemic on cancer assessment in primary care: a qualitative study of GP views. BJGP Open, 2021, doi: 10.3399/BJGPO.2021.0056
  35. Rubin G & Meyer A. Diagnostic errors and harms in primary care: insights to action. BMJ Quality & Safety, 2021, doi: 10.1136/bmjqs-2020-012423
  36. Holt Jessen N, Jensen H, Helsper CW, Falborg AZ, Glerup H, Gronbaek H, Vedsted P. Cancer suspicion, referral to cancer patient pathway and primary care interval: a survey and register study exploring 10 different types of abdominal cancer. Family Practice, 2021, cmab025, doi: 10.1093/fampra/cmab025
  37. Druce P, Calanzani N, Snudden C, et al. Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Lower Gastrointestinal Cancers: A Systematic Review and Meta-AnalysisAdv Ther, 2021.
  38. Achkar MA, Zigman Suchland M, Walter FM, Neal RD, Goulart BHL, Thompson MJ. Experiences along the diagnostic pathway for patients with advanced lung cancer in the USA: a qualitative study. BMJ Open, 2021; 11:e045056, doi: 10.1136/bmjopen-2020-045056
  39. Calanzani N, Chang A, Van Melle Marije, Pannebakker MM, Funston G, Walter FM. Recognising Colorectal Cancer in Primary Care. Advance in Therapy, 2021, 1-15, doi: 10.1007/s12325-021-01726-6
  40. Reece JC, Neal EFG, Nguyen P, McIntosh JG, Emery JD. Delayed or failure to follow-up abnormal breast cancer screening mammograms in primary care: a systematic review. BMC Cancer, 2021, 21:373, doi: 10.1186/s12885-021-08100-3
  41. Keeney E, Mohiuddin S, Zienius K, Ben-Shlomo Y, Ozawa M, Grant R, Hamilton W, Weller D, Brennan PM, Hollingworth W. Economic evaluation of GPs’ direct access to computed tomography for identification of brain tumours. European Journal of Cancer Care, 2020, doi: 10.1111/ecc.13345h
  42. Harries J, Scott SE, Walter FM, Mwaka AD, Moodley J. Women’s appraisal, interpretation and help-seeking for possible symptoms of breast and cervical cancer in South Africa: a qualitative study. BMC Women’s Health, 2020; 20: 251, doi: 10.1186/s12905-020-01120-4
  43. Nnaji CA, Kuodi P, Walter FM, Moodley J. Effectiveness of interventions for improving timely diagnosis of breast and cervical cancers in low and middle-income countries: a systematic review protocol. BMJ Open, 2020;10:e042788. doi: 10.1136/bmjopen-2020-042788
  44. Bradley SH, Hatton NLF, Aslam R, Bhartia B, Callister MEJ, Kennedy MPT, Mounce L, Shinkins B, Hamilton WT, Neal RD. Estimating lung cancer risk from chest x-ray and symptoms: a prospective cohort study. British Journal of General Practice, 2020, doi: 10.3399/bjgp20X713993
  45. Quiroga M, Shephard EA, Mounce LTA, Carney M, Hamilton WT, Price SJ. Quantifying the impact of pre-existing conditions on the stage of oesophagogastric cancer at diagnosis: a primary care cohort study using electronic medical records. Family Practice, 2020, doi: 10.1093/fampra/cmaa132
  46. Moodley J, Constant D, Mwaka AD, Scott SE, Walter FM. Anticipated help seeking behavior and barriers to seeking care for possible breast and cervical cancer symptoms in Uganda and South Africa. Ecancer, 2021, 15:1171, doi: 10.3332/ecancer.2021.1171
  47. Mills K, Paxton B, Walter FM, Griffin SJ, Sutton S, Usher-Smith JA. Incorporating a brief intervention for personalised cancer risk assessment to promote behaviour change into primary care: a multi-methods pilot study. BMC Public Health, 2021, 21:205, doi: 10.1186/s12889-021-10210-3
  48. Carver T, Hartley S, Lee A, Cunningham AP, Archer S, Babb de Villiers C, Roberts J, Ruston R, Walter FM, Tischkowitz M, Easton DF, Antoniou AC. CanRisk Tool – A web interface for the prediction of breast and ovarian cancer risk and the likelihood of carrying genetic pathogenic variants. Cancer Epidemiology, Biomarkers & Prevention, 2021, doi: 10.1158/1055-9965.EPI-20-1319
  49. Merriel SWD, Moon, D; Dunde, P; Corcoran, N; Carroll, P; Partin, A; Smith, J A; Hamdy, F; Moore, C; Ost, P; Costello, T. A modified Delphi study to develop a practical guide for selecting patients with prostate cancer for Active Surveillance. BMC Urology, 2021; 21:18, doi: 10.1186/s12894-021-00789-5
  50. Bradley SH, Thompson MJ, Nicholson BD. Ensuring informed decision-making for cancer screening. Journal of the American Board of Family Medicine, 2021, 34(2), doi: 10.3122/jabfm.2021.02.200353
  51. Barclay ME, Abel GA, Greenberg DC, Rous B, Lyratzopoulos G. The Socio-demographic variation in stage at diagnosis of breast, bladder, colon, endometrial, lung, melanoma, prostate, rectal, renal and ovarian cancer in England and its population impact. British Journal of Cancer, 2021, doi: 10.1038/s41416-021-01279-z
  52. Bradley SH, Shinkins B, Kennedy MP. What is the balance of benefits and harms for lung cancer screening with low-dose computed tomography? Journal of the Royal Society of Medicine, 2021, 114(4):164-170. doi: 10.1177/0141076821991108
  53. Holt Jessen N, Jensen H, Falborg AZ, Glerup H, Gronbaek H, Vedsted P. Abdominal investigations in the year preceding a diagnosis of abdominal cancer: a register-based cohort study in Denmark. Cancer Epidemiology, 2021, doi: 10.1016/j.canep.2021.101926
  54. Martins T, Merriel SWD, Hamilton W. Routes to diagnosis of symptomatic cancer in sub-Saharan Africa: systematic review. BMJ Open, 2020;10:e038605. doi: 10.1136/bmjopen-2020-038605
  55. Funston G, Mounce LTA, Price S, Rous B, Crosbie EJ, Hamilton W, Walter FM. CA125 test result, test-to-diagnosis interval and stage in ovarian cancer: a cohort study using electronic health records. BJGP, doi: 10.3399/BJGP.2020.0859
  56. Jones OT, Calanzani N, Saji S, Duffy SW, Emery J, Hamilton W, Singh H, de Wit NJ, Walter FM. Artificial Intelligence Techniques That May Be Applied to Primary Care Data to Facilitate Earlier Diagnosis of Cancer: Systematic ReviewJ Med Internet Res, 2021;23(3):e23483. doi: 10.2196/23483
  57. Forster AS, Rubin G, Emery J, Thompson M, Sutton S, de Wit N, Walter FM, Lyratzopoulos G. Measuring patient experience of diagnostic care and acceptability of testing. De Gruyter, 2021, doi: 10.1515/dx-2020-0112
  58. Herbert A, Barclay ME, Koo MM, Rous B, Greenberg DC, Abel G, Lyratzopoulos G. Stage–specific incidence trends of renal cancers in the East of England, 1999–2016. Cancer Epidemiology, 2021, 71(A), doi: 10.1016/j.canep.2020.101883
  59. Bradley SH & Barclay ME. “Liquid biopsy” for cancer screening. British Medical Journal, 2021; 372:m4933, doi: 10.1136/bmj.m4933
  60. Koo MM, Unger-Saldana K, Mwaka AD, Corbex M, Ginsburg O, Walter FM, Calanzani N, Moodley J, Rubin GP, Lyratzopoulos G. Conceptual Framework to Guide Early Diagnosis Programs for Symptomatic Cancer as Part of Global Cancer Control. JCO Global Oncology, 2021 Jan: 7:35-45, doi: 10.1200/GO.20.00310
  61. Funston G, Hardy V, Abel, G, Crosbie EJ, Emery J, Hamilton W, Walter FM. Identifying Ovarian Cancer in Symptomatic Women: A Systematic Review of Clinical Tools. Cancers 2020, 12, 3686. doi: 10.3390/cancers12123686
  62. Zhou Y, Walter FM, Singh H, Hamilton W, Abel GA, Lyratzopoulos. Prolonged Diagnostic Intervals as Marker of Missed Diagnostic Opportunities in Bladder and Kidney Cancer Patients with Alarm Features: A Longitudinal Linked Data Study. Cancers, 2021, 13(1): 156, doi: 10.3390/cancers13010156
  63. Bailey SER, Abel GA, Atkins A, Byford R, Davies S-J, Mays J, McDonald TJ, Miller J, Neck C, Rennison J, Thomas P, Walter FM, Warren S, Hamilton W. Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South West of England. British Journal of Cancer, 2021, doi: 10.1038/s41416-020-01221-9
  64. Arendse KD, Walter FM, Pilling M, Zhou Y, Hamilton W, Funston G. Time from presentation to pre-diagnostic chest X-ray in symptomatic lung cancer patients: a cohort study using electronic patient records. British Journal of General Practice, 2020, bjgp20X714077, doi: 10.3399/bjgp20X714077
  65. Calanzani N, Druce PE, Snudden C, Milley KM, Boscott R, Behiyat D, Saji S, Martinez Gutierrez J, Oberoi J, Funston G, Messenger M, Emery J, Walter FM. Identifying Novel Biomarkers Ready for Evaluation in Low-Prevalence Populations for the Early Detection of Upper Gastrointestinal Cancers: A Systematic Review. Adv Ther (2020). doi: 10.1007/s12325-020-01571-z
  66. Merriel SWD, Hamilton W. Improving early cancer diagnosis in primary care. Prescriber, 2020, 31:9, 10-14, doi: 10.1002/psb.1862
  67. Bradley SH, Richards GC, Lloyd K, Wayant C, DeVito N, Rombey T, Gill P. Reducing bias and improving transparency in medical research: A critical overview of the problems, progress so far and suggested next steps. Journal of Royal Society of Medicine, 2020,113(11):433-443, doi:10.1177/0141076820956799
  68. Koo MM, Swann R, McPhail S, Abel GA, Renzi C, Rubin GP, Lyratzopoulos G. The prevalence of chronic conditions in patients diagnosed with one of 29 common and rarer cancers: A cross-sectional study using primary care data. Cancer Epidemiology, 2020, 69: 101845, doi: 10.1016/j.canep.2020.101845
  69. Clarke C, Hamilton W, Price S, Bailey SER. Association of non-malignant diseases with thrombocytosis: a prospective cohort study in general practice. British Journal of General Practice, 2020, 70(701): e852-e857, doi: 10.3399/bjgp20X713501
  70. Funston G, Hamilton W, Abel G, Crosbie EJ, Rous B, Walter FM (2020) The diagnostic performance of CA125 for the detection of ovarian and non-ovarian cancer in primary care: A population-based cohort study. PLoS Med 17(10): e1003295. doi:10.1371/journal.pmed.1003295
  71. Moodley J, Constant D, Mwaka AD, Scott SE, Walter FM. Mapping awareness of breast and cervical cancer risk factors, symptoms and lay beliefs in Uganda and South Africa. PLOS One, 2020, doi: 10.1371/journal.pone.0240788
  72. van Erp NF, Helsper CW, Olyhoek SM, Janssen RRT, Winsveen A, Peeters PHM, de Wit NJ. Potential for reducing time to referral for colorectal cancer patients in primary care. Ann Fam Med, 2019, 17(5): 419-427, doi: 10.1370/afm.2446
  73. Koo MM, Lyratzopoulos G, Herbert A, Abel GA, Taylor RM, Barber JA, Gibson F, Whelan J, Fern LA. Association of Self-reported Presenting Symptoms With Timeliness of Help-Seeking Among Adolescents and Young Adults With Cancer in the BRIGHTLIGHT Study. JAMA Netw Open. 2020 Sep 1;3(9):e2015437. doi: 10.1001/jamanetworkopen.2020.15437
  74. Loveday C, Sud A, Jones ME, Broggio J, Scott S, Gronthound F, Torr B, Garrett A, Nicol DL, Jhanji S, Boyce SA, Williams M, Barry C, Riboli E, Kipps E, McFerran E, Muller DC, Lyratzopoulos G, Lawler M, Abulafi M, Houlston RS, Turnbull C. Prioritisation by FIT to mitigate the impact of delays in the 2-week wait colorectal cancer referral pathway during the COVID-19 pandemic: a UK modelling study. Gut, 2020, gutjnl-2020-321650. doi: 10.1136/gutjnl-2020
  75. Renzi C, Lyratzopoulos G. Comorbidity and the diagnosis of symptomatic-but-as-yet-undiagnosed cancer. Br J Gen Pract. 2020;70(698):e598-e599
  76. Helsper CW, Campbell C, Emery J, Neal RD, Li L, Rubin G, van Weert H, Vedsted P, Walter FM, Weller D, Nekhlyudov L. Cancer has not gone away: A Primary Care perspective to support a balanced approach for timely cancer diagnosis during COVID-19. Euro J Cancer Care, 2020, e13290, doi: 10.1111/ecc.13290
  77. van Erp NF, Helsper CW, Slottje P, Brandenbarg D, Büchner FL, van Asselt KM,Muris J, Kortekaas MF, Peeters P, de Wit NJ. Time to diagnosis of symptomatic gastric and oesophageal cancer in the Netherlands: Where is the room for improvement? United European Gastroenterol J, 2020, 8(5): 607-620, doi: 10.1177/2050640620917804
  78. Price S, Spencer A, Zhang X, Ball S, Lyratzopoulos, Mujica-Mota R, Stapley S, Ukoumunne OC, Hamilton W. Trends in time to cancer diagnosis around the period of changing national guidance on referral of symptomatic patients: A serial cross-sectional study using UK electronic healthcare records from 2006–17Cancer Epidemiology, 2020; 101805, doi: 10.1016/j.canep.2020.101805
  79. Kaushal A, Waller J, von Wagner C, Kummer S, Whitaker K, Puri A, Lyratzopoulos G, Renzi C. The role of chronic conditions in influencing symptom attribution and anticipated help-seeking for potential lung cancer symptoms: a vignette-based study. BJGP Open, 2020, doi: 10.3399/bjgpopen20X101086
  80. Atkin C, Iqbal G, Planche T, Pratt G, Yong K, Wood J, Raynes K, Low E, Higgins H, Neal RD, Dunn J, Drayson MT, Bowcock S. Diagnostic pathways in multiple myeloma and their relationship to end organ damage: an analysis from the Tackling Early Morbidity and Mortality in Myeloma (TEAMM) trial. British Journal of Haematology, 2020, doi: 10.1111/bjh.17044
  81. Jones OT, Calanzani N, Saji S, Duffy SW, Emery J, Hamilton W, Singh H, de Wit N, Walter F. Application of artificial intelligence to electronic health records for early detection and diagnosis of cancer in primary care: a Systematic Review. JMIR, 2020:23483, doi: 10.2196/preprints.23483
  82. Bright CJ, Gildea C, Lai J, Elliss-Brookes L, Lyratzopoulos G. Does geodemographic segmentation explain differences in route of cancer diagnosis above and beyond person-level sociodemographic variables? Journal of Public Health, 2020, fdaa111, doi: 10.1093/pubmed/fdaa111
  83. Fitzgerald RC, di Pietro M, O’Donovan M, Maroni R, Muldrew B, Debiram-Beecham I, Gehrung M, Offman J, Tripathi M, Smith SG, Aigret B, Walter FM, Rubin G, the BEST3 Trial Team, Sasieni P. Cytosponge-trefoil factor 3 versus usual care to identify Barrett’s oesophagus in a primary care setting: a multicentre, pragmatic, randomised controlled trial. The Lancet, 2020, 396(10247): 333-344, doi: 10.1016/S0140-6736(20)31099-0
  84. di Martino E, Ayaz-Shah A, Shinkins B, Jain S, Neal RD. A urine test for bladder cancer: available soon in primary care? Trends in Urology & Men’s Health, 2020, 11(4), doi: 10.1002/tre.760
  85. Mounce LTA, Hamilton W, Bailey SER. Cancer incidence following a high-normal platelet count: cohort study using electronic healthcare records from English primary care. British Journal of General Practice, 2020, doi: 10.3399/bjgp20X710957
  86. Sud A, Torr B, Jones ME, Broggio J, Scott S, Loveday C, Garrett A, Gronthoud F, Nicol DL, Jhanji S, Boyce SA, Williams M, Riboli E, Muller DC, Kipps E, Larkin J, Navani N, Swanton C, Lyratzopoulos G, McFerran E, Lawler M, Houlston R, Turnbull C. Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study. The Lancet Oncology, 2020, 21(8): 1035-1044, doi: 10.1016/S1470-2045(20)30392-2
  87. Saya S, McIntosh J, Winship I, Clendenning M, Milton S, Oberoi J, Dowty J, Buchanan D, Jenkins M, Emery J. A genomic test for colorectal cancer risk: is this acceptable and feasible in primary care? Public Health Genomics, 2020, doi: 10.1159/000508963
  88. Singh H, Sittig DF, Gandhi TK. Fighting a common enemy: a catalyst to close intractable safety gaps. BMJ Quality & Safety, 2020, doi: 10.1136/bmjqs-2020-011390
  89. Carney M, Quiroga M, Mounce L, Shephard E, Hamilton W, Price S. Effect of pre-existing conditions on bladder cancer stage at diagnosis: a cohort study using electronic primary care records in the UK. British Journal of General Practice, 2020; bjgp20X710921, doi: 10.3399/bjgp20X710921
  90. Chapman D, Poirier V, Vulkan D, Fitzgerald K, Rubin G, Hamilton W, Duffy SW. First results from five multidisciplinary diagnostic centre (MDC) projects for non-specific but concerning symptoms, possibly indicative of cancer. British Journal of Cancer, 2020, doi: 10.1038/s41416-020-0947-y
  91. di Martino E, Andersen AC, Mengel-Jørgensen T, Jensen MB, Bradley S, Neal RD. Is there a place for point-of-care ultrasound in UK primary care? British Journal of General Practice, 2020; 70 (696): 323-324. doi: 10.3399/bjgp20X710801
  92. Hopkins R, Bailey SER, Hamilton WT, Shephard EA. Microcytosis as a risk marker of cancer in primary care: a cohort study using electronic patient records. British Journal of General Practice, 2020; 70 (696): e457-e462. doi: 10.3399/bjgp20X709577
  93. Gandhi TK, Singh H. Reducing the Risk of Diagnostic Error in the COVID-19 Era. Journal of Hospital Medicine, 2020 June;15(6): 363-366, doi: 10.12788/jhm.3461
  94. Sarma EA, Kobrin SC, Thompson MJ. A Proposal to Improve the Early Diagnosis of Symptomatic Cancers in the US. Cancer Prevention Research, 2020, doi: 10.1158/1940-6207.CAPR-20-0115
  95. Sud A, Jones ME, Broggio J, Loveday C, Torr B, Garrett A, Nicol DL, Jhanji S, Boyce SA, Gronthoud F, Ward P, Handy JM, Yousaf N, Larkin J, Suh Y-E, Scott S, Pharoah PDP, Swanton C, Abbosh C, Williams M, Lyratzopoulos G, Houlston R, Turnbull C. Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic. Annals of Oncology, 2020, 31(8): 1065-1074, doi: 10.1016/j.annonc.2020.05.009
  96. Price S, Zhang X, Spencer A. Measuring the impact of national guidelines: What methods can be used to uncover time-varying effects for healthcare evaluations? Social Science and Medicine, 2020, 258(113021), doi: 10.1016/j.socscimed.2020.113021
  97. Cocco, P., Ayaz-Shah, A., Messenger, M.P. et al. Target Product Profiles for medical tests: a systematic review of current methods. BMC Medicine, 2020, 18(119), doi: 10.1186/s12916-020-01582-1
  98. Marije van Melle, Samir IS Yep Manzano, Hugh Wilson, Willie Hamilton,Fiona M Walter, Sarah ER Bailey. Faecal immunochemical test to triage patients with abdominal symptoms for suspected colorectal cancer in primary care: review of international use and guidelines. Family Practice, 2020. doi: 10.1093/fampra/cmaa043
  99. Sud A, Jones M, Broggio J, Scott S, Loveday C, Torr B, Garrett A, Nicol DL, Jhanji S, Boyce SA, Williams M, Lyratzopoulos G, Barry C, Riboli E, Kipps E, McFerran E, Lawler M, Muller DC, Abulafi M, Houlston R, Turnbull CA. Quantifying and mitigating the impact of the COVID-19 pandemic on outcomes in colorectal cancer. Gut, 2020, doi: 10.1101/2020.04.28.20083170
  100. Jones D, Neal RD, Duffy SRG, Scott SE, Whitaker KL, Brain K. Impact of the COVID-19 pandemic on the symptomatic diagnosis of cancer: the view from primary care. The Lancet Oncology, 2020, 21(6): 748-750, doi: 10.1016/S1470-2045(20)30242-4
  101. Zhou Y, Abel GA, Hamilton W, Singh H, Walter FM, Lyratzopoulos G. Imaging activity possibly signalling missed diagnostic opportunities in bladder and kidney cancer: A longitudinal data-linkage study using primary care electronic health records. Cancer Epidemiology, 2020, 66(101703), doi: 10.1016/j.canep.2020.101703
  102. Merriel SWD, Hardy V, Thompson M, Walter FM, Hamilton W. Patient-centered outcomes from multiparametric magnetic resonance imaging (mpMRI) and MRI-guided biopsy for prostate cancer: A systematic review. Journal of the American College of Radiology, 2020, 17(4): 486-495, doi: 10.1016/j.jacr.2019.08.031
  103. Lyratzopoulos G, Abel GA. Assessing patients at risk of symptomatic-but-as-yet-undiagnosed cancer in primary care using information from patient records. British Journal of Cancer, 2020 Jun;122(12):1729-1731. doi: 10.1038/s41416-020-0828-4
  104. Nicholson BD, Hamilton W, Koshiaris C, Oke JL, Hobbs R, Aveyard P. The association between unexpected weight loss and cancer diagnosis in primary care: a matched cohort analysis of 65,000 presentations. British Journal of Cancer, 2020, 122(12): 1848-1856, doi: 10.1038/s41416-020-0829-3
  105. Round T, Abel G. Seeing the wood and the trees: the impact of the healthcare system on variation in primary care referrals. BMJ Quality & Safety, 2020, 29:274-276, doi: 10.1136/bmjqs-2019-010356
  106. Rafiq M, Hayward A, Warren-Gash C, Denaxas S, Gonzalez-Izquierdo A, Lyratzopoulos G, Thomas S. Allergic disease, corticosteroid use, and risk of Hodgkin lymphoma: A United Kingdom nationwide case-control study. Journal of Allergy and Clinical Immunology, 2020, 145(3): 868-876, doi: 10.1016/j.jaci.2019.10.033
  107. Archer S, De Villiers CB, Scheibl F, Carver T, Hartley S, Lee A, Cunningham AP, Easton DF, McIntosh JG, Emery J, Tischkowitz M, Antoniou AC, Walter FM. Evaluating clinician acceptability of the prototype CanRisk tool for predicting risk of breast and ovarian cancer: A multi-methods study. PLoS ONE, 2020, 15(3): e0229999, doi: 10.1371/journal.pone.0229999
  108. Walter FM, Pannebakker MP, Barclay ME, Mills K, Saunders CL, Murchie P, Corrie P, Hall P, Burrows N, Emery JD. Effect of a Skin Self-monitoring Smartphone Application on Time to Physician Consultation Among Patients With Possible Melanoma: A Phase 2 Randomized Clinical Trial. JAMA Network Open, 2020, doi: 10.1001/jamanetworkopen.2020.0001
  109. Giadina TD, Royse KE, Khanna A, Haskell H, Hallisy J, Southwick F, Singh H. Health Care Provider Factors Associated with Patient-Reported Adverse Events and Harm. Joint Commission Journal on Quality and Patient Safety, 2020, 5: 282-290, doi: 10.1016/j.jcjq.2020.02.004
  110. Habgood E, Walter FM, O’Hare E, McIntosh J, McCormack C, Emery JD. Using an electronic self-completion tool to identify patients at increased risk of melanoma in Australian primary care. Austalasian Journal of Dermatology, 2020, doi: 10.1111/ajd.13244
  111. Chowienczyk S, Price S, Hamilton W. Changes in the presenting symptoms of lung cancer from 2000–2017: a serial cross-sectional study of observational records in UK primary care. British Journal of General Practice, 2020, 79(692): 193-199, doi: 10.3399/bjgp20X708137
  112. Pearson C, Poirier V, Fitzgerald K, Rubin G, Hamilton W. Cross-sectional study using primary care and cancer registration data to investigate patients with cancer presenting with non-specific symptoms. British Medical Journal Open, 2020, doi: 10.1136/bmjopen-2019-033008
  113. Swann R, Lyratzopoulos G, Rubin G, Pickworth E, McPhail S. The frequency, nature and impact of GP-assessed avoidable delays in a population-based cohort of cancer patients. Cancer Epidemiology, 2020, 64(101617), doi: 10.1016/j.canep.2019.101617
  114. Chima S, Reece JC, Milley K, Milton S, McIntosh JG, Emery J. Decision support tools to improve cancer diagnostic decision making in primary care: a systematic review. British Journal of General Practice, 2019, 69(689): e809-e818, doi: 10.3399/bjgp19X706745
  115. Jones OT, Ranmuthu CKI, Hall PN, Funston G, Walter F. Recognising Skin Cancer in Primary Care. Advances in Therapy, 2020, 37(1): 603-616, doi: 10.1007/s12325-019-01130-1
  116. Koo MM, Swann R, McPhail S, Abel GA, Elliss-Brookes L, Rubin GP, Lyratzopoulos G. Presenting symptoms of cancer and stage at diagnosis: evidence from a cross-sectional, population-based study. The Lancet Oncology, 2020, 21(1): 73-79, doi: 10.1016/S1470-2045(19)30595-9
  117. Funston G, Van Melle M, Ladegaard Baun M-L, Jensen H, Helsper C, Emery J, Crosbie EJ, Thompson M, Hamilton W, Walter F. Variation in the initial assessment and investigation for ovarian cancer in symptomatic women: a systematic review of international guidelines. BMC Cancer, 2019, 19:1028 doi:10.1186/s12885-019-6211-2
  118. Smith AF, Shinkins B, Hall PS, Hulme CT, Messenger MP. Towards a framework for outcome-based analytical performance specifications: a methodology review of indirect methods for evaluating the impact of measurement uncertainty on clinical outcomes. Clinical Chemistry, 65(11): 1363-1374, doi: 10.1373/clinchem.2018.300954
  119. Herbert A, Winters S, McPhail S, Elliss-Brookes L, Lyratzopoulos G, Abel G. Population trends in emergency cancer diagnoses: The role of changing patient case-mix. Cancer Epidemiology, 63:101574, doi: 10.1016/j.canep.2019.101574
  120. Bradley SH, Abraham S, Callister M, Grice A, Hamilton W, Rodriguez Lopez R, Shinkin B, Neal R. Sensitivity of chest x-ray for detecting lung cancer in people presenting with symptoms: systematic review. British Journal of General Practice, 2019, 69(689): e827-e835, doi: 10.3399/bjgp19X706853
  121. Watson J, Mounce L, Bailey SER, Cooper SL, Hamilton W. Blood markers for cancer. British Medical Journal, 2019, 367:l5774, doi: 10.1136/bmj.l5774
  122. Zhou Y, van Melle M, Singh H, Hamilton W, Lyratzopoulos G, Walter FM. Quality of the Diagnostic Process in Patients Presenting with Symptoms Suggestive of Bladder or Kidney Cancer: A Systematic Review. British Medical Journal Open, 2019, 9(10): e029143, doi: 10.1136/bmjopen-2019-029143
  123. Murphy DR., Giardina TD, Satterly T, Sittig DF, Singh H. An Exploration of Barriers, Facilitators, and Suggestions for Improving Electronic Health Record Inbox-Related Usability. A Qualitative Analysis. JAMA Network Open, 2019, 2(10):e1912638, doi:10.1001/jamanetworkopen.2019.12638
  124. Nicholson BD, Aveyard P, Hamilton W, Hobbs FDR. When should unexpected weight loss warrant further investigation to exclude cancer? British Medical Journal, 2019, 366:l5271, doi: 10.1136/bmj.l5271
  125. Koo MM, Rubin G, McPhail S, Lyratzopoulos G. Incidentally diagnosed cancer: population-based evidence on frequency, variation, and commonly preceding clinical scenarios. British Medical Journal Open, 2019, 9(9): e028362, doi: 10.1136/bmjopen-2018-028362
  126. Herbert A, Abel GA, Winters S, McPhail S, Elliss-Brookes L, Lyratzopoulos G. Cancer diagnoses after emergency GP referral or A&E attendance in England: Determinants and time trends in Routes to Diagnosis data, 2006–2015. British Journal of General Practice, 2019, bjgp19X705473, doi: 10.3399/bjgp19X705473
  127. Jones OT, Jurascheck LC, van Melle MA, Hickman S, Burrows NP, Hall PN, Emery J, Walter FM. Dermoscopy for melanoma detection and triage in primary care: a systematic review. British Medical Journal Open, 2019, 9:e027529, doi:10.1136/bmjopen-2018-027529
  128. Elwenspoek MMC, Sheppard AL, McInnes MDF, Merriel SWD, Rowe EWJ, Bryant RJ, Donovan JL, Whiting P. Comparison of multiparametric magnet resonance imaging and targeted biopsy with systematic biopsy alone for the diagnosis of prostate cancer: A systematic review and meta-analysis. JAMA Network Open, 2019, 2(8):e198427, doi: 10.1001/jamanetworkopen.2019.8427
  129. Moodley J, Scott SE, Mwaka AD, Constant D, Githaiga JN, Stewart TS, Payne A, Cairncross L, Somdyala NIM, Walter FM. Development and validation of the African Women Awareness of CANcer (AWACAN) tool for breast and cervical cancer. PLoS ONE, 2019, 14(8):e0220545, doi: 10.1371/journal.pone.0220545
  130. Renzi C, Kaushal A, Emery J, Hamilton W, Neal RD, Rachet B, Rubin G, Singh H, Walter FM, de Wit NJ, Lyratzopoulos G. Comorbid chronic diseases and cancer diagnosis: disease-specific effects and underlying mechanisms. Nature Reviews: Clinical Oncology, 2019, 16(12): 746-761, doi: 10.1038/s41571-019-0249-6
  131. Amelung D, Whitaker KL, Lennard D, Ogden M, Sheringham J, Zhou Y, Walter FM, Singh H, Vincent C, Black G. Influence of doctor-patient conversations on behaviours of patients presenting to primary care with new or persistent symptoms: a video observation study. British Medical Journal Quality & Safety, 2019, doi: 10.1136/bmjqs-2019-009485
  132. Singh H, Khanna K, Spitzmueller C, Meyer AND. Recommendations for using the Revised Safer Dx Instrument to help measure and improve diagnostic safety. Diagnosis, 2019. pii: /j/dx.ahead-of-print/dx-2019-0012/dx-2019-0012.xml. doi: 10.1515/dx-2019-0012
  133. Walter FM, Thompson MJ, Wellwood I, Abel GA, Hamilton W, Johnson M, Lyratzopoulos G, Messenger MP, Neal RD, Rubin G, Singh H, Spencer A, Sutton S, Vedsted P, Emery JD. Evaluating diagnostic strategies for early detection of cancer: the CanTest framework. BMC Cancer, 2019, 19:586, doi: 10.1186/s12885-019-5746-6
  134. Watson J, Jones HE, Banks J, Whiting P, Salisbury C, Hamilton W. Use of multiple inflammatory marker tests in primary care: using Clinical Practice Research Datalink to evaluate accuracy. British Journal of General Practice, 2019, 69(684): e662-e669, doi: 10.3399/bjgp19X704309
  135. Watson J, Salisbury C, Whiting P, Banks J, Pyne Y, Hamilton W. Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink. British Journal of General Practice, 2019, 69(684): e470-e478, doi: 10.3399/bjgp19X704321
  136. Pearson C, Fraser J, Peake M, Valori R, Poirier V, Coupland VH, Hiom S, McPhail S, Moffat J, Lyratzopoulos G, Shelton J. Establishing population-based surveillance of diagnostic timeliness using linked cancer registry and administrative data for patients with colorectal and lung cancer. Cancer Epidemiology, 2019, 61:111-118, doi: 10.1016/j.canep.2019.05.010
  137. Neal RD, Sun F, Emery JD, Callister ME. Lung Cancer. British Medical Journal, 2019, 365:I1725, doi: 10.1136/bmj.l1725
  138. Renzi C, Lyratzopoulos G, Hamilton W, Maringe C, Bernard R. Contrasting effects of comorbidities on emergency colon cancer diagnosis: a longitudinal data-linkage study in England. BMC Health Services Research, 2019; 19:311, doi: 10.1186/s12913-019-4075-4
  139. Baun ML, Jensen H, Falborg AZ, Heje HN, Petersen LK, Vedsted P. Ovarian cancer suspicion, urgent referral and time to diagnosis in Danish general practice: a population-based study. Family Practice, 2019, 36(6): 751-757, doi: 10.1093/fampra/cmz013
  140. Watson J, Salisbury C, Banks J, Whiting P, Hamilton W. Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records. British Journal of Cancer, 2019, 120:1045-1051, doi: 10.1038/s41416-019-0458-x
  141. Jones OT, Jurascheck LC, Utukuri M, Pannebakker MM, Emery J, Walter FM. Dermoscopy use in UK primary care: a survey of GPs with a special interest in dermatology. Journal of the European Academy of Dermatology and Venereology, 2019, doi: 10.1111/jdv.15614
  142. Murphy DR, Satterly T, Rogith D, Sittig DF, Singh H. Barriers and facilitators impacting reliability of the electronic health record-facilitated total testing process. International Journal of Medical Informatics, 2019, 127: 102-108, doi: 10.1016/j.ijmedinf.2019.04.004
  143. Zhou Y, Funston G, Lyratzopoulos G, Walter FM. Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care. Advances in Therapy, 2019, doi: 10.1007/s12325-019-00966-x
  144. Walter FM, Penfold C, Joannides A, Saji S, Johnson M, Watts C, Brodbelt A, Jenkinson MD, Price SJ, Hamilton W, Scott SE. Missed opportunities for diagnosing brain tumours in primary care: a qualitative study of patient experiences. British Journal of General Practice, 2019, bjgp19X701861. doi: 10.3399/bjgp19X701861
  145. Scott SE, Penfold C, Saji S, Curtis S, Watts C, Hamilton W, Joannides AJ, Walter FM. ‘It was nothing that you would think was anything’: Qualitative analysis of appraisal and help seeking preceding brain cancer diagnosis. PLoS ONE, 2019, 14:3, e02135, doi: 10.1371/journal.pone.0213599, doi: 10.1371/journal.pone.0213599
  146. Renzi C, Lyratzopoulos G, Hamilton W, Rachet B. Opportunities for reducing emergency diagnoses of colon cancer in women and men: a data-linkage study on pre-diagnostic symptomatic presentations and benign diagnoses. European Journal of Cancer Care, 2019. e13000. doi: 10.1111/ecc.13000
  147. Mendonca SC, Abel GA, Gildea C, McPhail S, Peake MD, Rubin G, Singh H, Hamilton W, Walter FM, Roland MO, Lyratzopoulos G. Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study. Family Practice, 2019, 36(5): 573-580, doi: 10.1093/fampra/cmy118
  148. Bradley SH, Kennedy MPT, Neal RD. Recognising Lung Cancer in Primary Care. Advances in Therapy, 2018, 36 (1):19-30, doi: 10.1007/s12325-018-0843-5
  149. Herbert A, Abel GA, Winters S, McPhail S, Elliss-Brookes L, Lyratzopoulos G. Are inequalities in cancer diagnosis through emergency presentation narrowing, widening or remaining unchanged? Longitudinal analysis of English population-based data 2006-2013. Journal of Epidemiology & Community Health, 2019, 73(1): 3-10, doi: 10.1136/jech-2017-210371
  150. Nicholson BD, Perera R, Thompson MJ. Editorials: The elusive diagnosis of cancer: Testing times. British Journal of General Practice, 2018, 68:676, 510-511, doi: 10.3399/bjgp18X699461
  151. Stanciu MA, Law R-J, Nafees S, Hendry M, Yeo ST, Hiscock J, Lewis R, Edwards RT, Williams NH, Brain K, Brocklehurst P, Carson-Stevens A, Dolwani S, Emery J, Hamilton W, Hoare Z, Lyratzopoulos G, Rubin G, Smits S, Vedsted P, Walter FM, Wilkinson C, Neal RD. Development of an intervention to expedite cancer diagnosis through primary care: Protocol. British Journal of General Practice Open, 2018, 2 (3): bjgpopen18X101595, doi: 10.3399/bjgpopen18X101595
  152. Lyratzopoulos G. Electronic patient records research to aid diagnostic reasoning for possible cancer in primary care. British Journal of General Practice, 2018; 68 (674): 408-409, doi: 10.3399/bjgp18X698585
  153. Maringe C, Rachet B, Lyratzopoulos G, Rubio FJ. Persistent inequalities in unplanned hospitalisation among colon cancer patients across critical phases of their care pathway, England, 2011–13. British Journal of Cancer, 2018, 119:5, 551-557, doi: 10.1038/s41416-018-0170-2
  154. Herbert A, Koo MM, Barclay ME, Greenberg DC, Abel GA, Levell NJ, Lyratzopoulos G. Stage-specific incidence trends of melanoma in an English region, 1996–2015: longitudinal analyses of population-based data. Melanoma Research, 2018. doi: 10.1097/CMR.0000000000000489
  155. Forster AS, Renzi C, Lyratzopoulos G. Diagnosing cancer in patients with ‘non-alarm’ symptoms: Learning from diagnostic care innovations in Denmark. Cancer Epidemiology, 2018; 54, 101-103, doi: 10.1016/j.canep.2018.03.011
  156. Salika T, Abel GA, Mendonca SC, von Wagner C, Renzi C, Herbert A, McPhail S, Lyratzopoulos G. Associations between diagnostic pathways and care experience in colorectal cancer: evidence from patient-reported data. Frontline Gastroenterology 2018;9:241-248, doi: 10.1136/flgastro-2017-100926
  157. Kwan JL, Singh H. General Internists in Pursuit of Diagnostic Excellence in Primary Care: a #ProudtobeGIM Thread That Unites Us All. Journal of General Internal Medicine, 33(4): 395-396, doi: 10.1007/s11606-018-4343-8
  158. Ozawa M, Brennan PM, Zienius K, Kurian KM, Hollingworth W, Weller D, Hamilton W, Grant R, Ben-Shlomo Y. Symptoms in primary care with time to diagnosis of brain tumours. Family Practice, 2018: 1-8, doi: 10.1093/fampra/cmx139
  159. Rubin G, Walter F, Emery J, and de Wit N. Reimagining the diagnostic pathway for gastro-intestinal cancer. Nature Reviews Gastroenterology and Hepatology, 2018; 15: 181-188, doi: 10.1038/nrgastro.2018.1
  160. Herbert A, Lyratzopoulos G., Whelan J., Taylor R.M., Barber J., Gibson F., Fern L.A. Diagnostic timeliness in adolescents and young adults with cancer: a cross-sectional analysis of the BRIGHTLIGHT cohort. The Lancet Child and Adolescent Health, 2018; 2(3): 180-190, doi: 10.1016/S2352-4642(18)30004-X