Publications

Below is a list of all CanTest publications that acknowledge the support of Cancer Research UK:

  1. Round T, Abel G. Seeing the wood and the trees: the impact of the healthcare system on variation in primary care referrals. BMJ Quality & Safety, 2019, 0:1-3, doi: 10.1136/bmjqs-2019-010356
  2. Swann R, Lyratzopoulos G, Rubin G, Pickworth E, McPhail S. The frequency, nature and impact of GP-assessed avoidable delays in a population-based cohort of cancer patients. Cancer Epidemiology, 2019, doi: 10.1016/j.canep.2019.101617
  3. Chima S, Reece JC, Milley K, Milton S, McIntosh JG, Emery J. Decision support tools to improve cancer diagnostic decision making in primary care: a systematic review. British Journal of General Practice, 2019, doi: 10.3399/bjgp19X706745
  4. Jones OT, Ranmuthu CKI, Hall PN, Funston G, Walter F. Recognising Skin Cancer in Primary Care. Advances in Therapy, 2019, 1-14, doi: 10.1007/s12325-019-01130-1
  5. Koo MM, Swann R, McPhail S, Abel GA, Elliss-Brookes L, Rubin GP, Lyratzopoulos G. Presenting symptoms of cancer and stage at diagnosis: evidence from a cross-sectional, population-based study. The Lancet Oncology, 2019, doi: 10.1016/S1470-2045(19)30595-9
  6. Funston G, Van Melle M, Ladegaard Baun M-L, Jensen H, Helsper C, Emery J, Crosbie EJ, Thompson M, Hamilton W, Walter F. Variation in the initial assessment and investigation for ovarian cancer in symptomatic women: a systematic review of international guidelines. BMC Cancer, 2019, 19:1028 doi:10.1186/s12885-019-6211-2
  7. Smith AF, Shinkins B, Hall PS, Hulme CT, Messenger MP. Towards a framework for outcome-based analytical performance specifications: a methodology review of indirect methods for evaluating the impact of measurement uncertainty on clinical outcomesClinical Chemistry,65:11 (1363-1374), doi: 10.1373/clinchem.2018.300954
  8. Herbert A, Winters S, McPhail S, Elliss-Brookes L, Lyratzopoulos G, Abel G. Population trends in emergency cancer diagnoses: The role of changing patient case-mix. Cancer Epidemiology, 63, doi: 10.1016/j.canep.2019.101574
  9. Bradley SH, Abraham S, Callister M, Grice A, Hamilton W, Rodriguez Lopez R, Shinkin B, Neal R. Sensitivity of chest x-ray for detecting lung cancer in people presenting with symptoms: systematic review. British Journal of General Practice, 2019, doi: 10.3399/bjgp19X706853
  10. Watson J, Mounce L, Bailey SER, Cooper SL, Hamilton W. Blood markers for cancer. British Medical Journal, 2019, 367:l5774, doi: 10.1136/bmj.l5774
  11. Zhou Y, van Melle M, Singh H, Hamilton W, Lyratzopoulos G, Walter FM. Quality of the Diagnostic Process in Patients Presenting with Symptoms Suggestive of Bladder or Kidney Cancer: A Systematic Review. British Medical Journal Open, 2019, 2019;9:e029143. doi: 10.1136/bmjopen-2019-029143
  12. Nicholson BD, Aveyard P, Hamilton W, Hobbs FDR. When should unexpected weight loss warrant further investigation to exclude cancer? British Medical Journal, 2019, 366:l5271, doi: 10.1136/bmj.l5271
  13. Merriel SWD, Hardy V, Thompson M, Walter FM, Hamilton W. Patient-centered outcomes from multiparametric magnetic resonance imaging (mpMRI) and MRI-guided biopsy for prostate cancer: A systematic review. Journal of the American College of Radiology, 2019, S1546-1440(19)31032-4
  14. Singh H, Khanna K, Spitzmueller C, Meyer AND. Recommendations for using the Revised Safer Dx Instrument to help measure and improve diagnostic safety. Diagnosis, 2019. pii: /j/dx.ahead-of-print/dx-2019-0012/dx-2019-0012.xml. doi: 10.1515/dx-2019-0012
  15. Koo MM, Rubin G, McPhail S, Lyratzopoulos G. Incidentally diagnosed cancer: population-based evidence on frequency, variation, and commonly preceding clinical scenarios. BMJ Open, 2019, 9:e028362
  16. Herbert A, Abel GA, Winters S, McPhail S, Elliss-Brookes L, Lyratzopoulos G. Cancer diagnoses after emergency GP referral or A&E attendance in England: Determinants and time trends in Routes to Diagnosis data, 2006–2015. BJGP, 2019, bjgp19X705473
  17. Jones OT, Jurascheck LC, van Melle MA, Hickman S, Burrows NP, Hall PN, Emery J, Walter FM. Dermoscopy for melanoma detection and triage in primary care: a systematic review. BMJ Open, 2019, 9:e027529
  18. Elwenspoek MMC, Sheppard AL, McInnes MDF, Merriel SWD, Rowe EWJ, Bryant RJ, Donovan JL, Whiting P. Comparison of multiparametric magnetic resonance imaging and targeted biopsy with systematic biopsy alone for the diagnosis of prostate cancer: A systematic review and meta-analysis. JAMA Network Open, 2019, 2(8):e198427
  19. Moodley J, Scott SE, Mwaka AD, Constant D, Githaiga JN, Stewart TS, Payne A, Cairncross L, Somdyala NIM, Walter FM. Development and validation of the African Women Awareness of CANcer (AWACAN) tool for breast and cervical cancer. PLoS ONE, 2019, 14(8):e0220545
  20. Renzi C, Kaushal A, Emery J, Hamilton W, Neal RD, Rachet B, Rubin G, Singh H, Walter FM, de Wit NJ, Lyratzopoulos G. Comorbid chronic diseases and cancer diagnosis: disease-specific effects and underlying mechanisms. Nature Reviews: Clinical Oncology, 2019, https://doi.org/10.1038/s41571-019-0249-6
  21. Amelung D, Whitaker KL, Lennard D, Ogden M, Sheringham J, Zhou Y, Walter FM, Singh H, Vincent C, Black G. Influence of doctor-patient conversations on behaviours of patients presenting to primary care with new or persistent symptoms: a video observation study. BMJ Quality & Safety, https://doi.org/10.1136/bmjqs-2019-009485
  22. Walter FM, Thompson MJ, Wellwood I, Abel GA, Hamilton W, Johnson M, Lyratzopoulos G, Messenger MP, Neal RD, Rubin G, Singh H, Spencer A, Sutton S, Vedstead P, Emery JD. Evaluating diagnostic strategies for early detection of cancer: the CanTest framework. BMC Cancer, 2019, 19:586
  23. Pearson C, Fraser J, Peake M, Valori R, Poirier V, Coupland VH, Hiom S, McPhail S, Moffat J, Lyratzopoulos G, Shelton J. Establishing population-based surveillance of diagnostic timeliness using linked cancer registry and administrative data for patients with colorectal and lung cancer. Cancer Epidemiology, 2019, 61:111-118
  24. Neal RD, Sun F, Emery JD, Callister ME. Lung Cancer. BMJ, 2019, 365:I1725
  25. Renzi C, Lyratzopoulos G, Hamilton W, Maringe C, Bernard R. Contrasting effects of comorbidities on emergency colon cancer diagnosis: a longitudinal data-linkage study in England. BMC Health Services Research, 2019; 19:311
  26. Baun ML, Jensen H, Falborg AZ, Heje HN, Petersen LK, Vedsted P. Ovarian cancer suspicion, urgent referral and time to diagnosis in Danish general practice: a population-based study. Family Practice, 2019, cmz013
  27. Watson J, Salisbury C, Banks J, Whiting P, Hamilton W. Predictive value of inflammatory markers for cancer diagnosis in primary care: a prospective cohort study using electronic health records. British Journal of Cancer, 2019, 120:1045-1051
  28. Jones OT, Jurascheck LC, Utukuri M, Pannebakker MM, Emery J, Walter FM. Dermoscopy use in UK primary care: a survey of GPs with a special interest in dermatology. Journal of the European Academy of Dermatology and Venereology, 2019, https://doi.org/10.1111/jdv.15614
  29. Murphy DR, Satterly T, Rogith D, Sittig DF, Singh H. Barriers and facilitators impacting reliability of the electronic health record-facilitated total testing process. International Journal of Medical Informatics, 2019, 127: 102-108
  30. Zhou Y, Funston G, Lyratzopoulos G, Walter FM. Improving the Timely Detection of Bladder and Kidney Cancer in Primary Care. Advances in Therapy, 2019, https://doi.org/10.1007/s12325-019-00966-x
  31. Walter FM, Penfold C, Joannides A, Saji S, Johnson M, Watts C, Brodbelt A, Jenkinson MD, Price SJ, Hamilton W, Scott SE. Missed opportunities for diagnosing brain tumours in primary care: a qualitative study of patient experiences. Br J Gen Pract, 2019, bjgp19X701861. DOI: 10.3399/bjgp19X70186
  32. Scott SE, Penfold C, Saji S, Curtis S, Watts C, Hamilton W, Joannides AJ, Walter FM. ‘It was nothing that you would think was anything’: Qualitative analysis of appraisal and help seeking preceding brain cancer diagnosis. PLoS ONE, 2019, 14:3, e02135
  33. Renzi C, Lyratzopoulos G, Hamilton W, Rachet B. Opportunities for reducing emergency diagnoses of colon cancer in women and men: a data-linkage study on pre-diagnostic symptomatic presentations and benign diagnoses. Eur Journal Cancer Care. 2019. e13000. doi: 10.1111/ecc.13000
  34. Mendonca SC, Abel GA, Gildea C, McPhail S, Peake MD, Rubin G, Singh H, Hamilton W, Walter FM, Roland MO, Lyratzopoulos G. Associations between general practice characteristics with use of urgent referrals for suspected cancer and endoscopies: a cross-sectional ecological study. Family Practice, 2018, cmy118
  35. Bradley SH, Kennedy MPT, Neal R. Recognising Lung Cancer in Primary Care. Advances in Therapy 2018; 1-12
  36. Herbert A, Abel GA, Winters S, McPhail S, Elliss-Brookes L, Lyratzopoulos G. Are inequalities in cancer diagnosis through emergency presentation narrowing, widening or remaining unchanged? Longitudinal analysis of English population-based data 2006-2013. J Epidemiol Community Health, 2019, 73(1): 3-10
  37. Nicholson BD, Perera R, Thompson MJ. Editorials: The elusive diagnosis of cancer: Testing times. British Journal of General Practice, 2018, 68:676, 510-511
  38. Stanciu MA, Law R-J, Nafees S, Hendry M, Yeo ST, Hiscock J, Lewis R, Edwards RT, Williams NH, Brain K, Brocklehurst P, Carson-Stevens A, Dolwani S, Emery J, Hamilton W, Hoare Z, Lyratzopoulos G, Rubin G, Smits S, Vedsted P, Walter FM, Wilkinson C, Neal RD. Development of an intervention to expedite cancer diagnosis through primary care: Protocol. BJGP Open 4 September 2018; bjgpopen18X101595
  39. Lyratzopoulos G. Electronic patient records research to aid diagnostic reasoning for possible cancer in primary care. Br J Gen Pract 2018; 68 (674): 408-409
  40. Maringe C, Rachet B, Lyratzopoulos G, Rubio FJ. Persistent inequalities in unplanned hospitalisation among colon cancer patients across critical phases of their care pathway, England, 2011–13. British Journal of Cancer, 2018, 119:5, 551-557
  41. Herbert A, Koo MM, Barclay ME, Greenberg DC, Abel GA, Levell NJ, Lyratzopoulos G. Stage-specific incidence trends of melanoma in an English region, 1996–2015: longitudinal analyses of population-based data. Melanoma Research, 2018. doi: 10.1097/CMR.0000000000000489
  42. Forster AS, Renzi C, Lyratzopoulos G. Diagnosing cancer in patients with ‘non-alarm’ symptoms: Learning from diagnostic care innovations in Denmark. Cancer Epidemiology, 2018; 54, 101-103
  43. Salika T, Abel GA, Mendonca SC, von Wagner C, Renzi C, Herbert A, McPhail S, Lyratzopoulos G. Associations between diagnostic pathways and care experience in colorectal cancer: evidence from patient-reported data. Frontline Gastroenterology 2018;9:241-248
  44. Kwan JL, Singh H. General Internists in Pursuit of Diagnostic Excellence in Primary Care: a #ProudtobeGIM Thread That Unites Us All. Journal of General Internal Medicine, 33(4): 395-396
  45. Ozawa M, Brennan PM, Zienius K, Kurian KM, Hollingworth W, Weller D, Hamilton W, Grant R, Ben-Shlomo Y. Symptoms in primary care with time to diagnosis of brain tumours. Family Practice, 2018: 1-8
  46. Rubin G, Walter F, Emery J, and de Wit N. Reimagining the diagnostic pathway for gastro-intestinal cancer. Nature Reviews Gastroenterology and Hepatology, 2018; doi:10.1038/nrgastro.2018.1
  47. Herbert A, Lyratzopoulos G., Whelan J., Taylor R.M., Barber J., Gibson F., Fern L.A. Diagnostic timeliness in adolescents and young adults with cancer: a cross-sectional analysis of the BRIGHTLIGHT cohort. The Lancet Child and Adolescent Health, 2018; 2(3): 180-190