Projects

This page provides details about the portfolio of CanTest projects. In order to form part of the programme, projects must be approved via a two-stage scientific peer review process. This includes assessment against the following principles:

  1. The current diagnostic process in primary care is a problem
  2. Improving the triaging and diagnostic process related to (1) may have value to patients and society by having a potential impact on the morbidity, mortality, patient experience or healthcare utilisation of patients with and without cancer
  3. There is at least promising evidence from Phase 1 or later phases of the CanTest Framework, or research from other settings
  4. The diagnostic process is potentially feasible in community or primary care settings

Below you can find out more information about our current projects:

Can dermoscopy be used accurately and effectively in primary care to improve the timely diagnosis of melanoma?

A systematic review of existing research focusing on whether dermoscopes, with suitable training, can be used accurately and effectively by GPs, to improve early diagnosis of melanoma. Read more

Multi-parametric magnetic resonance imaging (mpMRI) for prostate cancer diagnosis in primary care

This PhD project will explore a number of areas relating to whether it would be safe, acceptable, and cost effective for GPs to order MRI scans for men with symptoms suggesting a possible diagnosis of prostate cancer. Read more

Establishing the diagnostic accuracy of haemoglobin in faecal immunochemical tests (FITs) in the primary care symptomatic population: A multicentre cohort study

This project will collect data to see how well FITs perform at diagnosing colorectal cancer in the primary care population, and to recommend a Hb level for further diagnostic testing when patients have a positive FIT. Read more

Understanding missed diagnostic opportunities in bladder and kidney cancer

This PhD project will use bladder and kidney cancer as exemplars to identify missed diagnostic opportunities in early cancer diagnosis. Read more

What is the clinical-effectiveness and cost-effectiveness of embedded risk-of-cancer assessment of patients in primary care: The ERICA trial

This is a cluster-randomised controlled clinical trial of electronic clinical decision support tools for six different cancer types in 710 English general practices. Read more

International dataset inventory for the CanTest collaborative

This project aims to create a simple repository with detailed information on the data available, and linkage possibilities, as well as its applicability for potential use in relation to key CanTest research objectives. Read more

Conceptualising and measuring patient experience in the diagnosis of cancer

This project will aim to explore the theory that a lack of evidence exploring how to optimally measure patient experience of diagnostic tests and strategies reflects a lack of appropriate conceptual frameworks and robust measurement tools about the patient experience of diagnostic tests. Read more

The role of imaging in the diagnosis of symptomatic lung cancer

This project focuses on lung cancer as a leading cause of death world wide. In the UK survival for patients diagnosed with lung cancer has been worse than for patients in many countries in Europe and North America. This project will compare data on tests and lung cancer from different countries. Read more

The diagnostic utility of inflammatory markers in primary care: a prospective cohort study

This project aims to find out whether blood tests called ‘inflammatory markers’ could help GPs to diagnose cancer. We will also look at whether they are useful for other important illnesses, such as infections and autoimmune conditions. Read more

The diagnostic utility of inflammatory markers in primary care: a prospective cohort study

In this multi-stage project, we will use routinely collected data to map how patients with ovarian cancer are currently evaluated and investigated in UK primary care, prior to diagnosis. Read more